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दुर्लभ विकार के लिए दवा दाद वायरस के इलाज के लिए वादा दिखाती है

By ice

दुर्लभ विकार के लिए दवा दाद वायरस के इलाज के लिए वादा दिखाती है 

पत्रिका साइंस एडवांस में प्रकाशित एक नए अध्ययन के अनुसार, एक दुर्लभ एंजाइम की कमी का इलाज करने के लिए वर्तमान में निर्धारित दवा से हर्पीज सिम्प्लेक्स 1 और हर्पीज सिम्प्लेक्स 2 वायरस को साफ करने में मदद मिल सकती है। नए डेटा से पता चलता है कि दवा की एंटीवायरल गतिविधि - जिसे फिनाइलब्यूटाइरेट, या पीबीए कहा जाता है - एससीक्लोविर, एक सामान्य एचएसवी -1 उपचार के साथ-साथ उपयोग किए जाने पर भी बेहतर था। जब संयोजन में उपयोग किया जाता है, तो अकेले एसाइक्लोविर की तुलना में वायरस को प्रभावी ढंग से दबाने के लिए कम एसाइक्लोविर की आवश्यकता होती है - यह महत्वपूर्ण है क्योंकि एसाइक्लोविर को गुर्दे में विषाक्त दुष्प्रभावों के लिए भी जाना जाता है। दाद सिंप्लेक्स वायरस दो प्रकार के होते हैं: हरपीज सिंप्लेक्स 1, जो आंखों और मुंह को संक्रमित करता है और अंधापन का एक प्रमुख कारण है, और हरपीज सिंप्लेक्स 2, एक जननांग संक्रमण है जो दर्दनाक घावों का कारण बन सकता है और जीवन की गुणवत्ता को गंभीर रूप से बिगाड़ सकता है। दोनों संक्रमणों के लिए उपचार में अक्सर एसाइक्लोविर शामिल होता है - मौखिक रूप से ली गई एक प्रणालीगत दवा। हालांकि, लंबे समय तक उपयोग से अक्सर दवा के प्रतिरोध के साथ-साथ गुर्दे की क्षति भी होती है। शुक्ला और उनके सहयोगियों ने पीबीए के एंटीवायरल प्रभावों की जांच की और पाया कि कोशिकाओं में दवा प्रोटीन का उत्पादन करने के लिए इस्तेमाल किए जाने वाले सेल्युलर मशीनरी को हाईजैक करने की क्षमता को बाधित करती है। आम तौर पर, वायरस कोशिकाओं को संक्रमित करते हैं और उन्हें वायरल प्रोटीन का उत्पादन करने के लिए मजबूर करते हैं ताकि वायरस खुद को दोहरा सके।


Drug 

Phenylbutyrate 

Treatment 

Simplex 

 वीडियो 

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